Alves F RA, Granato L, Maia M S. Acessos Cirúrgicos no Angiofibroma Nasofaríngeo Juvenil – Relato de caso e revisão de literatura. Arch Otolaryngol Head. Juvenile angiofibroma (JNA) is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males. Transcript of ANGIOFIBROMA JUVENIL NASOFARINGEO. Estadio I – tumor confinado a la nasofaríngeo. Estadio II – tumor extendido a la.

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The tumor is primarily excised by external or endoscopic approach. The other 17 patients required only endoscopic surgery.

Nasopharyngeal angiofibroma: Our experience and literature review

To retrospectively describe our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma. External carotid clamping has been shown to assist in hemostasis of the tumor. Sign up for our Email Newsletters. Intracranial juvenile nasopharyngeal angiofibroma. For example, a retrospective study of 15 patients found tumor recurrence in 1 patient 6.

Nasopharyngeal angiofibroma

National Center for Biotechnology InformationU. Case 1 Case 1. Although these masses are thought to arise from the region of the sphenopalatine foramenthey are usually sizeable at diagnosis, frequently with extension medially into the nasopharynxlaterally into the pterygopalatine fossa and over time beyond, into the orbitparanasal sinusesintracranial cavity and infratemporal fossa.

The tumor is limited to the sphenopalatine foramen, nasopharynx, and nasal cavity without bone destruction. All patients were male, and all had symptoms of progressive nasal obstruction and recurrent epistaxis. Vascularization arises most frequently from the maxillary artery i. Removal is important in preventing nasal obstruction and recurrent epistaxis. Transcatheter arterial embolization in nasopharyngeal angiofibroma.

Intracranial juvenile nasopharyngeal angiofibroma.

It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. In addition, preoperative embolization may complicate the identification of the full extent of surgical margins by reducing the tumor size and increasing the risk of relapse Jasofaringeo J Clin Oncol. Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma. However, as in any invasive procedure, embolization presents risks that should be fully explained to the patients Angiofibroma – rewiew of cases.


Endoscopic surgery alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages. Similarly, our patients ranged in age from 10 to 29 years, nasofarlngeo a mean age of 16 years, and all were male.

The third patient with a Fisch I tumor underwent surgery with embolization, but without clamping of the external carotid arteries. In this study, we have described our experience angiofibfoma treating 20 patients with nasopharyngeal angiofibromas in the Department of Otorhinolaryngology. Although nasal endoscopic surgery is safe, rapid, and effective, studies are needed to assess the importance of preoperative embolization and clamping of the external carotid artery in reducing intraoperative bleeding.

Services on Demand Journal. Recent advances in the treatment of juvenile angiofibroma. The tumors are frequently located in the posterolateral wall of the nasal cavity, where the sphenoid process of the palatine angiofibrima articulates with the base of the pterygoid process, forming the sphenopalatine foramen.

Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness ranging from single layer of endothelium to variable smooth muscle coat Irregular fibrous stroma loose, edematous to dense, acellular Stromal cells are stellate fibroblasts with small pyknotic to large vesicular nuclei Juvemil vessels at base of lesion, smaller vessels with plump endothelial cells at growing jjvenil of tumor Multinucleated stromal cells are common Mitotic figures are rare Minimal inflammation.

Computed tomography of a year-old patient with a Fisch class IIIa juvenile nasopharyngeal angiofibroma.

Non-surgical treatments are available, including the use of hormones estrogen, testosteroneradiation therapy, chemotherapy, and recently, embolization; however, surgery is considered the treatment of choice, with the route depending on the stage of the tumor and the overall condition of the patient 11 12 Discussion Juvenile nasopharyngeal angiofibromas present almost exclusively in men aged years Sanchez de Guzman G. Since then, several cases have been reported, all showing that endoscopic resection resulted in lower morbidity during the early stages of disease nasofagingeo Tumors may invade the anterior fossa through the ethmoid and sphenoid sinuses, being more frequent in the middle fossa and remaining extradural 8 9 Tumor size was not associated with bleeding.


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ANGIOFIBROMA JUVENIL NASOFARINGEO by renzo paredes terrones on Prezi

Nasopharyngeal angiofibroma is a angioflbroma and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal obstruction 1 2 3 4 5. Patients undergoing embolization require external carotid clamping due to collateral circulation, which can increase bleeding. Non-small-cell lung jasofaringeo Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma.

Preoperative embolisation of tumour may be of some use in reducing intraoperative bleeding. Juveinl Laser-assisted excision of juvenile nasopharyngeal angiofibromas. Sociedade Brasileira de Otorrinolaringologia. Synonyms or Alternate Spellings: Examinations such as computed tomography, nuclear magnetic resonance and even nasal endoscopy can clearly establish the extent of the tumor, its pattern of spread, and consequently, surgical planning 10,11,12,16,17,18, We also found that patients who underwent clamping of the external carotid artery and embolization showed less intraoperative bleeding than patients who underwent embolization alone.

Improvements in surgical techniques are designed to shorten surgical time and thereby reduce patient morbidity.